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Asam Salisilat: Manfaat, Dosis, Efek Samping

Binance Review 2018: Comprehensive Crypto Coin Exchange Binance is a Chinese cryptocurrency exchange. Binance was created after attracting funds via an ICO (Initial Coin Offering – creating a new digital asset, backed by the project. Changpeng Zhao, former CTO at OKCoin is currently at the helm of Binance. They are known for fast processing speeds coupled with an ability to process enormous numbers of transactions (1.4 million) each second. It’s been quickly gaining ground in market share cementing a place as a top 20 exchange in terms of volume. Binance transaction has reached a new level and currently score tenth place in the world. Binance offers a generous daily withdrawal limit. They don’t need identity confirmation when the per day remittance is within limit of 2 BTC. Binance Features Binance’s trading platform is web-based. Furthermore it offers two distinct trading layouts, a more simple one and a “Pro” version. Their ICO has created tokens named BNB that are traded on the exchange. They can also be used as a method of paying your trading fees, which will reduce them by 50%. Binance offers their own startup incubator platform as well. The trading functionality of the platform was of more interest so we focused on that for the purposes of this Binance review. Below is the “standard platform” look: Below is the advanced display: BINANCE Advantages Large Cryptocurrency Pairings Supported The competitive advantage of Binance’s platform is the ability to trade every major cryptocurrency pairing in existence. Coinbase and Gemini only offer trading of a handful of the larger market capitalization cryptos, whereas Binance allows users access to trade over 100 crypto coins. Low Fees AND LIMITS The fee structure is simple as well as being priced. There is a flat 0.10% fee on all trading. The 0.10% fee on trades is one basis point. If you were to buy a cryptocoin at 100 you’d have to sell it higher for 101 to profit. Ease of Setup Setting up an account is straight forward, similar to signing up for an account with other service providers. Another advantage is there is no lengthy waiting time, users are able to get setup and running within minutes. This is due to the fact that fiat is not accepted on the exchange. Binance Provides Significant Trading Volume Binance is currently the third largest exchange by cryptocurrency trading volume, according to coinmarketcap. At the time of writing, Binance’s volume was an astounding $5,441,711,452 in the last 24 hours! This volume demonstrates their users clear trust in the exchange, as well as the accessibility of the exchange and ease of transacting. This type of volume requires substantial servers and computational power. Wide Support of Cryptocurrencies No Verification Requirements Binance doesn’t require identity confirmation in instances when the per day remittance is within the limit of 2 BTC. The attractiveness of setting up an account with Binance may be greater for a user in a jurisdiction where certain exchanges choose not to allow new users because of restrictions imposed by that location’s governing regulatory bodies. Ease of Use You’re able to buy and sell crypto pairings with market or limit orders while specifying the amount or percentage you wish to trade for each transaction. BINANCE Disadvantages No Leveraged Margin Trading Margin trading is not available at Binance. Margin trading is a system which allows you to trade with more money than you actually have in your account. Your balance is then used as a guarantee to maintain your position open. No Fiat Functionality This has both advantages and disadvantages. Government fiat deposits are not currently enabled in Binance, instead this exchange focuses only on the digital side of things. Clients can deposit and withdraw the coins supported at the exchange. This means that you’re not able to deposit or withdraw in fiat currency, only cryptocurrency is supported. Relatively New Binance was started in only July 2017, according to this Reddit post. This is a major concern, as they don’t have a history. Despite all the good things people are saying on Reddit. it’s worth mentioning as many exchanges have come and gone. Binance appears to have a visible co-founder, unlike BTC-E. Conclusion Accessible option for obtaining Different Cryptocoins Binance is the most rapidly-growing and communally praised cryptocurrency exchange available. It’s China based location may spell issues in the future due to rumors of a “crackdown“. that currently accounts for a large amount of volume. Although Binance targets high frequency traders, it is quite useful for those getting beginning with altcoin trading. Their lack of fiat money deposits may be difficult to swallow for beginners, only supported cryptocurrencies may be deposited. Binance boasts a large number of various cryptocoins for trading. The main benefit is the ability convert between cryptocurrencies. For instance exchanges such as Coinbase and Gemini are more limited in the number of cryptocurrencies offered. The interface is also conducive to support shorter duration hold time day trading of cryptocurrencies if one were so inclined to deploy that strategy. Binance is an exchange worth looking into and integrating into crypto trading just for their large amount of supported crypto coins.
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asam-salisilat-doktersehat

DokterSehat.Com – Asam salisilat obat apa? Asam salisilat adalah obat yang digunakan untuk mengatasi beberapa jenis masalah kulit. Ketahui lebih jauh tentang asam salisilat mulai dari manfaat, dosis, efek samping, dan lainnya tentang asam salisilat berikut ini.

Cara Kerja Obat

Asam salisilat masuk ke dalam golongan obat keratolitik. Apa itu keratolitik? Keratolitik adalah zat agen yang dapat melunakkan lapisan keratin pada kulit. Agen ini bekerja mengatasi masalah kulit dengan cara membantu pengelupasan sel-sel kulit.

Manfaat Asam Salisilat

Kegunaan asam salisilat secara umum adalah untuk mengatasi masalah kulit. Berikut adalah beberapa indikasi asam salisilat:

  • Psoriasis
  • Iktiosis
  • Ketombe
  • Kapalan
  • Mata ikan
  • Kutil di tangan atau kaki
  • Mengatasi jerawat dan mencegah jerawat muncul kembali

Meskipun mengatasi kutil menjadi salah satu fungsi asam salisilat, namun asam salisilat tidak dapat digunakan untuk kutil kelamin, kutil pada wajah, kutil yang ditumbuhi rambut, kutil pada hidung, kutil pada mulut, tahi lalat, dan tanda lahir.

Dosis Asam Salisilat

Asam salisilat tersedia dalam beberapa bentuk sediaan mulai dari krim, gel, lotion, sampo, salep, cairan, dan masih banyak bentuk lainnya. Dosis asam salisilat tentunya disesuaikan dengan sediaan dan juga dengan kondisi yang akan diobati.

Berikut adalah beberapa dosis asam salisilat yang disarankan dari sediaan yang paling umum ditemukan:

1. Dosis asam salisilat krim topikal

  • Mata ikan: krim 2-10%, gunakan sesuai kebutuhan. Gunakan krim 25-60% setiap 3 hingga 5 hari sekali.
  • Jerawat: gel 0,5-5%, gunakan satu kali sehari.
  • Psoriasis: gunakan gel 5%, satu kali sehari.
  • Kutil: gunakan gel 5-26%, satu kali sehari.

2. Dosis asam salisilat lotion

  • Jerawat: lotion 1-2%, gunakan sebanyak 1-3 kali per hari.
  • Ketombe: lotion 1,8-2%, gunakan sebanyak 1-3 kali per hari.

3. Dosis asam salisilat salep

  • Jerawat: salep 3-6% sesuai kebutuhan.
  • Psoriasis dan ketombe: salep 3-10% sesuai kebutuhan.
  • Kutil: salep 3-10%, gunakan sesuai kebutuhan. Salep 25-60%, gunakan satu kali setiap 3 hingga 5 hari.

Petunjuk Penggunaan Asam Salisilat

Penggunaan obat asam salisilat sebaiknya digunakan sesuai dengan aturannya. Berikut adalah petunjuk penggunaan asam salisilat:

  • Asam salisilat digunakan sebagai obat topikal yang hanya dapat digunakan untuk penggunaan luar.
  • Gunakan obat sesuai dengan petunjuk penggunaan menyesuaikan dengan sediaan yang digunakan.
  • Gunakan obat sesuai dengan dosis yang disarankan.
  • Hindari penggunaan obat pada area sensitif seperti mata, hidung, mulut, dan mukosa.
  • Jika tidak sengaja menelan asam salisilat, segera hubungi penyedia layanan kesehatan.

Petunjuk Penyimpanan Asam Salisilat

Berikut adalah petunjuk penyimpanan asam salisilat yang harus diperhatikan:

  • Simpan asam salisilat pada suhu di bawah 25°C.
  • Simpan obat asam salisilat di tempat kering dan tidak lembap, jangan simpan di kamar mandi.
  • Hindari obat asam salisilat dari cahaya atau sinar matahari langsung.
  • Hindari obat asam salisilat dari jangkauan anak-anak dan hewan peliharaan.
  • Jika obat sudah memasuki masa expired, jangan buang obat sembarangan, diskusikan dengan apoteker tentang petunjuk pembuangan obat ini.

Efek Samping Asam Salisilat

Obat-obatan jenis apapun berpotensi menimbulkan efek samping, begitu juga dengan Asam Salisilat. Beberapa efek samping yang mungkin timbul dari obat asam salisilat adalah sebagai berikut ini:

  • Iritasi kulit
  • Sensasi terbakar pada kulit

Efek samping lain yang lebih serius namun lebih sering terjadi adalah:

  • Kebingungan
  • Pusing
  • Kelelalah
  • Sakit kepala
  • Nafas cepat
  • Dengung pada telinga
  • Gangguan pendengaran
  • Mual
  • Muntah
  • Diare

Efek samping berupa reaksi alergi juga mungkin muncul berupa:

  • Gatal
  • Tenggorokan sesak
  • Kesulitan bernafas
  • Lemas
  • Pembengkakan pada mata, wajah, bibir, dan lidah

Efek samping di atas tidak selalu terjadi. Efek samping dapat terjadi akibat penggunaan obat berlebihan, interaksi obat, penggunaan jangka panjang, atau karena kondisi tertentu dari setiap pasien yang tentunya berbeda-beda.

Jika Anda merasakan gejala efek samping serius atau reaksi alergi, segera diskusikan dengan dokter untuk mendapatkan penanganan lebih lanjut dan hentikan penggunaan obat.

Interaksi Obat Asam Salisilat

Interaksi obat dapat terjadi ketika asam salisilat digunakan bersama dengan jenis obat-obatan lain tertentu. Interaksi obat menyebabkan efektivitas obat menurun dan dapat meningkatkan potensi terjadinya efek samping.

Berikut adalah jenis obat yang sebaiknya tidak digunakan bersama dengan asam salisilat:

  • Adapalene topikal
  • Benzoyl peroxide topika
  • Alitretinoin topikal
  • Clindamycin
  • Hydroquinone
  • Mequinol
  • Isotretinoin
  • Tretinoin topikal
  • Tazarotene

Daftar obat di atas kemungkinan bukan merupakan daftar lengkap. Beri tahu dokter apabila Anda sedang menggunakan atau belakangan menggunakan obat-obatan tertentu. Konsumsi alkohol juga dapat menyebabkan interaksi obat, maka sebaiknya dihindari.

Diskusikan juga dengan dokter tentang jenis makanan atau minuman yang sebaiknya dihindari selama penggunaan obat asam salisilat untuk menghindari interaksi obat.

Peringatan dan Perhatian Asam Salisilat

Asam salisilat termasuk ke dalam jenis obat bebas yang penggunaannya tidak harus melalui resep dokter. Berikut adalah beberapa hal lain yang perlu menjadi peringatan dan perhatian selama penggunaan obat asam salisilat:

  • Jangan gunakan asam salisilat pada pasien yang hipersensitif terhadap asam salisilat dan komponen lain yang terkandung dalam obat. Beri tahu dokter jika Anda memiliki riwayat alergi jenis obat tertentu seperti obat antiinflamasi nonsteroid (OAINS).
  • Hati-hati penggunaan pada pasien yang memiliki kondisi diabetes, penyakit pembuluh darah, gangguan ginjal, dan gangguan hati.
  • Penggunaan asam salisilat pada anak usia di bawah 2 tahun tidak disarankan, sebaiknya diskusikan lebih dulu dengan dokter tentang penggunaannya.
  • Beri tahu dokter jika Anda sedang hamil, sedang merencanakan kehamilan atau sedang menyusui. Jika Anda hamil ketika sedang menjalani pengobatan dengan obat ini, segera beri tahu dokter.

 

Sumber:

  1. Salicylic Acid (Topical Route) – https://www.mayoclinic.org/drugs-supplements/salicylic-acid-topical-route/precautions/drg-20066030 diakses 10 April 2019
  2. Salicylic acid topical Drug Interactions – https://www.drugs.com/drug-interactions/salicylic-acid-topical.html diakses 10 April 2019
  3. Salicylic Acid Topical – https://medlineplus.gov/druginfo/meds/a607072.html diakses 10 April 2019


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