Binance Review 2018: Comprehensive Crypto Coin Exchange
Binance is a Chinese cryptocurrency exchange. Binance was created after attracting funds via an ICO (Initial Coin Offering – creating a new digital asset, backed by the project. Changpeng Zhao, former CTO at OKCoin is currently at the helm of Binance. They are known for fast processing speeds coupled with an ability to process enormous numbers of transactions (1.4 million) each second. It’s been quickly gaining ground in market share cementing a place as a top 20 exchange in terms of volume.
Binance transaction has reached a new level and currently score tenth place in the world. Binance offers a generous daily withdrawal limit. They don’t need identity confirmation when the per day remittance is within limit of 2 BTC.
Binance Features
Binance’s trading platform is web-based. Furthermore it offers two distinct trading layouts, a more simple one and a “Pro” version.
Their ICO has created tokens named BNB that are traded on the exchange. They can also be used as a method of paying your trading fees, which will reduce them by 50%. Binance offers their own startup incubator platform as well. The trading functionality of the platform was of more interest so we focused on that for the purposes of this Binance review.
Below is the “standard platform” look:
Below is the advanced display:
BINANCE Advantages
Large Cryptocurrency Pairings Supported
The competitive advantage of Binance’s platform is the ability to trade every major cryptocurrency pairing in existence. Coinbase and Gemini only offer trading of a handful of the larger market capitalization cryptos, whereas Binance allows users access to trade over 100 crypto coins.
Low Fees AND LIMITS
The fee structure is simple as well as being priced. There is a flat 0.10% fee on all trading. The 0.10% fee on trades is one basis point. If you were to buy a cryptocoin at 100 you’d have to sell it higher for 101 to profit.
Ease of Setup
Setting up an account is straight forward, similar to signing up for an account with other service providers. Another advantage is there is no lengthy waiting time, users are able to get setup and running within minutes. This is due to the fact that fiat is not accepted on the exchange.
Binance Provides Significant Trading Volume
Binance is currently the third largest exchange by cryptocurrency trading volume, according to coinmarketcap. At the time of writing, Binance’s volume was an astounding $5,441,711,452 in the last 24 hours! This volume demonstrates their users clear trust in the exchange, as well as the accessibility of the exchange and ease of transacting. This type of volume requires substantial servers and computational power.
Wide Support of Cryptocurrencies
No Verification Requirements
Binance doesn’t require identity confirmation in instances when the per day remittance is within the limit of 2 BTC. The attractiveness of setting up an account with Binance may be greater for a user in a jurisdiction where certain exchanges choose not to allow new users because of restrictions imposed by that location’s governing regulatory bodies.
Ease of Use
You’re able to buy and sell crypto pairings with market or limit orders while specifying the amount or percentage you wish to trade for each transaction.
BINANCE Disadvantages
No Leveraged Margin Trading
Margin trading is not available at Binance. Margin trading is a system which allows you to trade with more money than you actually have in your account. Your balance is then used as a guarantee to maintain your position open.
No Fiat Functionality
This has both advantages and disadvantages. Government fiat deposits are not currently enabled in Binance, instead this exchange focuses only on the digital side of things. Clients can deposit and withdraw the coins supported at the exchange. This means that you’re not able to deposit or withdraw in fiat currency, only cryptocurrency is supported.
Relatively New
Binance was started in only July 2017, according to this Reddit post. This is a major concern, as they don’t have a history. Despite all the good things people are saying on Reddit. it’s worth mentioning as many exchanges have come and gone. Binance appears to have a visible co-founder, unlike BTC-E.
Conclusion
Accessible option for obtaining Different Cryptocoins
Binance is the most rapidly-growing and communally praised cryptocurrency exchange available. It’s China based location may spell issues in the future due to rumors of a “crackdown“. that currently accounts for a large amount of volume. Although Binance targets high frequency traders, it is quite useful for those getting beginning with altcoin trading. Their lack of fiat money deposits may be difficult to swallow for beginners, only supported cryptocurrencies may be deposited. Binance boasts a large number of various cryptocoins for trading.
The main benefit is the ability convert between cryptocurrencies. For instance exchanges such as Coinbase and Gemini are more limited in the number of cryptocurrencies offered. The interface is also conducive to support shorter duration hold time day trading of cryptocurrencies if one were so inclined to deploy that strategy. Binance is an exchange worth looking into and integrating into crypto trading just for their large amount of supported crypto coins.
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DokterSehat.Com – Colchicine obat apa? Colchicine adalah obat yang digunakan untuk mengatasi penyakit gout atau asam urat. Namun, obat colchicine tidak bisa menyembuhkan penyakit asam urat. Apabila Anda ingin menggunakan colchicine untuk meredakan nyeri dan tindak pencegahan, maka penjelasan ini bermanfaat untuk Anda.
Baca terus untuk mengetahui lebih lanjut tentang obat colchicine termasuk informasi tentang bentuk sediaan colchicine, kandungan colchicine, colchicine harga, indikasi colchicine, kontraindikasi colchicine, manfaat colchicine, dosis colchicine, dan efek samping colchicine.
Rangkuman Informasi Obat Colchicine
- Nama : Colchicine atau Kolkisin
- Golongan Obat : Obat Gout dan Hiperurisemia Karena Induksi Sitotoksik
- Bentuk Sediaan : Tablet
- Contoh merk : Recolfar
- Colchicine harga : Rp60.000-65.000 per strip (10 tablet)
- Manfaat : Mencegah gout dan meredakan nyeri gout akut
- Indikasi Penggunaan : Profilaksis gout dan nyeri karena gout
- Kontraindikasi : Kehamilan dan hipersensitivitas
- Dosis : 1,5-10 mg per hari (tergantung kasus medis)
- Cara pakai : Oral
- Efek samping : Mual, muntah, sakit perut, diare, dan lainnya
Bentuk Sediaan Colchicine
Bentuk sediaan colchicine sama seperti kebanyakan obat, yaitu berupa tablet. Setiap satu tablet colchicine mengandung dosis sebanyak 0,5 mg. Simpanlah obat colchicine di tempat yang sejuk dan kering.
Selain itu, jangan menyimpan obat colchicine di tempat yang terbuka sehingga mudah terkena paparan sinar matahari terus menerus. Paparan sinar matahari secara terus menerus bisa mengubah struktur dan manfaat bahan aktif colchicine.
Cara Kerja Kolkisin
Colchicine atau kolkisin merupakan nama dari bahan aktif obat. Cara kerja colchicine adalah dengan memengaruhi cara tubuh sehingga bisa merespons kristal asam urat dengan baik.
Respons tubuh yang baik dalam menangani kristal asam urat bisa membantu penekanan rasa nyeri dan bengkak yang terjadi pada penyakit gout. Hal ini juga bisa bermanfaat sebagai tindak pencegahan penyakit asam urat.
Baca Juga: Gout Arthritis: Gejala, Penyebab, Diagnosis dan Pengobatan
Colchicine Harga
Berapa harga obat colchicine? Harga colchicine adalah Rp60.000-65.000 per strip. Setiap satu strip berisi 10 tablet. Jadi, harga tiap tablet colchicine adalah Rp6.000-6.500 per tablet. Setiap satu dos berisi 3 strip sehingga kisaran colchicine harga adalah Rp180.000-200.000 per dos.
Indikasi Colchicine
Penggunaan obat kolkisin tidak boleh sembarangan karena bisa menimbulkan efek samping tertentu. Gunakanlah obat colchicine jika memiliki indikasi medis. Obat colchicine bisa digunakan jika Anda ingin mencegah penyakit gout atau asam urat dalam jangka pendek.
Obat colchicine juga bisa digunakan pada penderita penyakit gout akut dengan tujuan untuk meredakan dan menghilangkan rasa nyeri yang muncul ketika ada serangan gout secara tiba-tiba atau berat.
Colchicine juga diindikasikan untuk mengurangi gejala sindrom Behcets. Gejala sindorm Behcets tersebut seperti pembengkakan, kemerahan, kehangatan, dan rasa sakit. Orang-orang yang mengalami demam Mediterania familial bisa menggunakan obat kolkisin.
Kontraindikasi Colchicine
Meskipun Anda ingin mencegah penyakit gout atau ingin mengurangi rasa nyeri akibat serangan gout, Anda tidak bisa menggunakan colchicine jika memiliki hal-hal yang menjadi kontraindikasi.
Wanita yang sedang hamil tidak boleh menggunakan obat colchicine. Hal ini dikarenakan cara kerja obat colchicine bisa memengaruhi kondisi fisiologis pada ibu hamil yang berakibat fatal pada janin dan kondisi kehamilan.
Penggunaan obat colchicine juga dikontraindikasikan bagi orang-orang yang memiliki riwayat hipersensitivitas atau alergi terhadap obat-obatan yang mengandung colchicine. Ini dikarenakan colchicine bisa memicu terjadinya reaksi alergi.
Peringatan Penggunaan Obat Colchicine
Sebelum menggunakan obat colchicine sebaiknya Anda memerhatikan beberapa hal. Ada beberapa kondisi tertentu yang membuat Anda harus berhati-hati di dalam menggunakan obat colchicine.
Berikut ini adalah beberapa hal yang harus diperhatikan sebelum menggunakan colchicine:
- Berhati-hati jika ingin diberikan pada ibu menyusui, lansia, dan anak-anak
- Berhati-hati jika menderita gangguan fungsi hati, ginjal, dan jantung
- Berhati-hati jika sedang menjalani terapi obat tertentu seperti ketoconazole, nefazodone, digoxin, obat-obat HIV
- Tidak boleh digunakan sebagai obat penghilang rasa sakit rutin untuk kondisi lain
Manfaat Colchicine
Manfaat obat colchicine umumnya memiliki kaitan erat dengan penyakit gout atau asam urat. Inilah mengapa obat colchicine termasuk ke dalam obat antigout atau agen antigout. Namun, manfaat colchicine juga bisa mengatasi masalah medis selain gout.
Obat colchicine bermanfaat untuk mencegah terjadinya asam urat pada orang dewasa. Manfaat colchicine juga bisa meredakan rasa nyeri akibat serangan penyakit gout secara mendadak dan cukup berat.
Colchicine juga bisa mengatasi kasus sindorm Behcets dan demam Mediterania familial. Akan tetapi, manfaat colchicine yang satu itu tidak populer dikarenakan sindrom Behcets dan demam Mediterani familial tidak lazim terjadi.
Dosis Colchicine
Jika Anda ingin mendapatkan manfaat obat colchicine, maka minumlah colchicine sesuai dengan dosis yang dianjurkan. Dosis colchicine biasanya tertera pada kemasan. Anda juga bisa minum obat colchicine sesuai dengan dosis yang dianjurkan oleh dokter.
Dosis colchicine di awal adalah 1 mg dan diikuti dengan dosis 500 mcg setiap 2-3 jam. Gunakan dosis tersebut hingga rasa nyeri tidak terasa. Anda juga bisa menggunakan dosis tersebut hingga dosis total mencapai 10 mg.
Tindakan profilaksis gout atau pencegahan penyakit asam urat memerlukan dosis colchicine sejumlah 500 mcg sebanyak 2-3 kali dalam sehari. Dosis profilaksis tersebut perlu dikombinasikan dengan alopurinol atau urikosurik.
Baca Juga: Nilai Normal dan Nilai Tidak Normal Asam Urat
Efek Samping Colchicine
Pemakaian obat colchicine bisa menimbulkan efek samping tertentu mulai dari efek samping yang paling umum terjadi hingga efek samping yang cukup serius. Efek samping colchicine yang paling umum terjadi berupa sakit perut, diare, mual, dan muntah.
Namun, jika Anda mengalami diare berat, maka itu dikarenakan penggunaan obat colchicine yang melebihi dosis atau overdosis. Obat colchicine juga bisa menimbulkan efek samping seperti ruam, gangguan ginjal, kelainan darah, miopati, pendarahan pada saluran cerna, dan alopesia.
Ada juga beberapa efek samping yang serius akibat penggunaan obat colchicine. Efek samping colchicine yang cukup serius, yaitu nyeri otot, jari-jari mati rasa, memar atau pendarahan yang tidak wajar, demam, infeksi, dan memucatnya bagian tubuh tertentu.
Orang-orang yang alergi terhadap kolkisin bisa mengalami reaksi alergi. Reaksi alergi ditandai dengan adanya ruam, gatal-gatal, sesak napas, sakit perut, sakit kepala atau pusing, mual, dan muntah.
Jika Anda mengalami efek samping yang telah disebutkan, maka hentikanlah segera pengobatan dengan obat colchicine. Segeralah mengunjungi rumah sakit atau klinik terdekat sehingga Anda bisa mendapatkan penanganan medis yang tepat dan cepat.
Sumber:
- PIONAS-BPOM: Kolkisin. http://pionas.pom.go.id/monografi/kolkisin [diakses pada 4 April 2019]
- Us National Library of Medicine: Colchicine. https://medlineplus.gov/druginfo/meds/a682711.html [diakses pada 4 April 2019]
- Drugs: Colchicine. https://www.drugs.com/mtm/colchicine.html [diakses pada 4 April 2019]
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