Binance Review 2018: Comprehensive Crypto Coin Exchange
Binance is a Chinese cryptocurrency exchange. Binance was created after attracting funds via an ICO (Initial Coin Offering – creating a new digital asset, backed by the project. Changpeng Zhao, former CTO at OKCoin is currently at the helm of Binance. They are known for fast processing speeds coupled with an ability to process enormous numbers of transactions (1.4 million) each second. It’s been quickly gaining ground in market share cementing a place as a top 20 exchange in terms of volume.
Binance transaction has reached a new level and currently score tenth place in the world. Binance offers a generous daily withdrawal limit. They don’t need identity confirmation when the per day remittance is within limit of 2 BTC.
Binance Features
Binance’s trading platform is web-based. Furthermore it offers two distinct trading layouts, a more simple one and a “Pro” version.
Their ICO has created tokens named BNB that are traded on the exchange. They can also be used as a method of paying your trading fees, which will reduce them by 50%. Binance offers their own startup incubator platform as well. The trading functionality of the platform was of more interest so we focused on that for the purposes of this Binance review.
Below is the “standard platform” look:
Below is the advanced display:
BINANCE Advantages
Large Cryptocurrency Pairings Supported
The competitive advantage of Binance’s platform is the ability to trade every major cryptocurrency pairing in existence. Coinbase and Gemini only offer trading of a handful of the larger market capitalization cryptos, whereas Binance allows users access to trade over 100 crypto coins.
Low Fees AND LIMITS
The fee structure is simple as well as being priced. There is a flat 0.10% fee on all trading. The 0.10% fee on trades is one basis point. If you were to buy a cryptocoin at 100 you’d have to sell it higher for 101 to profit.
Ease of Setup
Setting up an account is straight forward, similar to signing up for an account with other service providers. Another advantage is there is no lengthy waiting time, users are able to get setup and running within minutes. This is due to the fact that fiat is not accepted on the exchange.
Binance Provides Significant Trading Volume
Binance is currently the third largest exchange by cryptocurrency trading volume, according to coinmarketcap. At the time of writing, Binance’s volume was an astounding $5,441,711,452 in the last 24 hours! This volume demonstrates their users clear trust in the exchange, as well as the accessibility of the exchange and ease of transacting. This type of volume requires substantial servers and computational power.
Wide Support of Cryptocurrencies
No Verification Requirements
Binance doesn’t require identity confirmation in instances when the per day remittance is within the limit of 2 BTC. The attractiveness of setting up an account with Binance may be greater for a user in a jurisdiction where certain exchanges choose not to allow new users because of restrictions imposed by that location’s governing regulatory bodies.
Ease of Use
You’re able to buy and sell crypto pairings with market or limit orders while specifying the amount or percentage you wish to trade for each transaction.
BINANCE Disadvantages
No Leveraged Margin Trading
Margin trading is not available at Binance. Margin trading is a system which allows you to trade with more money than you actually have in your account. Your balance is then used as a guarantee to maintain your position open.
No Fiat Functionality
This has both advantages and disadvantages. Government fiat deposits are not currently enabled in Binance, instead this exchange focuses only on the digital side of things. Clients can deposit and withdraw the coins supported at the exchange. This means that you’re not able to deposit or withdraw in fiat currency, only cryptocurrency is supported.
Relatively New
Binance was started in only July 2017, according to this Reddit post. This is a major concern, as they don’t have a history. Despite all the good things people are saying on Reddit. it’s worth mentioning as many exchanges have come and gone. Binance appears to have a visible co-founder, unlike BTC-E.
Conclusion
Accessible option for obtaining Different Cryptocoins
Binance is the most rapidly-growing and communally praised cryptocurrency exchange available. It’s China based location may spell issues in the future due to rumors of a “crackdown“. that currently accounts for a large amount of volume. Although Binance targets high frequency traders, it is quite useful for those getting beginning with altcoin trading. Their lack of fiat money deposits may be difficult to swallow for beginners, only supported cryptocurrencies may be deposited. Binance boasts a large number of various cryptocoins for trading.
The main benefit is the ability convert between cryptocurrencies. For instance exchanges such as Coinbase and Gemini are more limited in the number of cryptocurrencies offered. The interface is also conducive to support shorter duration hold time day trading of cryptocurrencies if one were so inclined to deploy that strategy. Binance is an exchange worth looking into and integrating into crypto trading just for their large amount of supported crypto coins.
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DokterSehat.Com – Istilah diabetes lebih populer dikenal sebagai penyakit kencing manis. Namun pada dasarnya terdapat beberapa kondisi lain yang disebut diabetes, salah satunya adalah diabetes insipidus. Kondisi ini termasuk kondisi yang langka, kenali lebih jauh tentang penyebab, gejala, pengobatan, dan pencegahan penyakit diabetes insipidus.
Apa Itu Diabetes Insipidus?
Diabetes insipidus adalah kondisi di mana seseorang terus merasa haus dan menyebabkan produksi urin yang berlebih dari tubuh. Hal ini disebabkan oleh ketidakseimbangan cairan dalam tubuh. Diabetes insipidus adalah kondisi yang termasuk langka dan dapat terjadi pada siapa saja. Penyakit diabetes insipidus dapat menjadi penyakit bawaan maupun didapat.
Penyebab Diabetes Insipidus
Penyebab diabetes insipidus adalah akibat gangguan pada anti-diuretic hormone (ADH) atau yang memiliki nama lain vasopressin (AVP). Hormon ini diproduksi di hipotalamus yang ada di otak. Setelah itu vasopressin akan disimpan di kelenjar pituitari hingga dibutuhkan. Kelenjar ini terdapat di belakang pangkal hidung, di bawah otak Anda.
Vasopressin atau AVP bertugas untuk mengatur kadar cairan dalam tubuh dengan cara mengontrol kadar urine yang dihasilkan oleh ginjal. Kelenjar pituitari akan melepaskan AVP ketika tingkat air dalam tubuh menurun, sehingga tubuh menghemat air dan menghentikan produksi urin.
Penyebab diabetes insipidus adalah karena AVP tidak mampu untuk mengatur dengan baik tingkat air dalam tubuh, sehingga terlalu banyak urin yang diproduksi dan dikeluarkan dari tubuh. Terdapat dua jenis diabetes insipidus dan kedua jenis penyakit ini memiliki pemicu yang berbeda.
Jenis Diabetes Insipidus
Secara umum terdapat dua jenis diabetes insipidus yaitu diabetes insipidus kranial dan diabetes insipidus nefrogenik. Berikut adalah penjelasan dari kedua jenis diabetes insipidus tersebut:
1. Diabetes insipidus kranial
Diabetes insipidus kranial disebut juga diabetes insipidus sentral adalah jenis diabetes insipidus yang paling sering ditemui. Diabetes insipidus kranial terjadi ketika hipotalamus tidak memproduksi AVP dalam jumlah yang cukup sehingga produksi urin tidak dapat dicegah dan tubuh kehilangan air dalam jumlah berlebihan.
Berikut adalah beberapa kondisi yang menyebabkan diabetes insipidus kranial:
- Tumor otak yang menyebabkan kerusakan pada hipotalamus atau kelenjar pituitari.
- Cedera kepala berat yang menyebabkan kerusakan hipotalamus atau kelenjar pituitari
- Komplikasi yang terjadi akibat operasi otak atau kelenjar pituitari.
Sebanyak sepertiga kasus diabetes insipidus kranial tidak ditemukan penyebabnya. Kondisi ini termasuk sebagai idiopatik. Diduga penyebabnya terkait dengan sistem kekebalan tubuh yang menyerang sel normal yang memproduksi AVP, namun hingga kini belum diketahui alasan mengapa sistem imun menyerang sel tersebut.
Terdapat kondisi lain yang mungkin menyebabkan diabetes insipidur kranial, namun tidak terlalu umum seperti:
- Kanker dari bagian tubuh tertentu yang menyebar hingga otak
- Sindrom wolfram
- Kerusakan otak akibat hilangnya suplai oksigen (akibat stroke atau tenggelam)
- Infeksi otak seperti meningitis atau ensefalitis
2. Diabetes insipidus nefrogenik
Diabetes insipidus nefrogenik adalah kondisi di mana produksi AVP tidak terganggu, tetapi ginjal tidak dapat memberikan respons normal pada AVP. Diabetes insipidus jenis ini dapat merupakan penyakit bawaan atau didapat.
Berikut adalah penyebab diabetes insipidus nefrogenik:
- Mutasi gen AVPR2 atau AQP2 menyebabkan diabetes insipidus nefrogenik bawaan.
- Penggunaan lithium jangka panjang
- Hiperkalsemia
- Hipokalemia
- Infeksi ginjal
- Obstruksi ureter
Gejala Diabetes Insipidus
Diabetes insipidus ditandai dengan beberapa gejala seperti berikut ini:
- Rasa haus yang berlebihan
- Produksi urin encer dalam jumlah besar
- Sering ingin buang air kecil di malam hari
- Keinginan untuk minum minuman dingin lebih tinggi
Penderita diabetes insipidus dapat mengeluarkan urin sebanyak 19-20 liter per hari, kondisi ini termasuk kondisi yang serius. Umumnya orang dewasa hanya memproduksi urin sebanyak 1-2 liter saja per hari.
Gejala diabetes insipidus pada bayi dan anak sedikit berbeda dengan orang dewasa. Berikut adalah gejala diabetes insipidus pada bayi dan anak-anak:
- Popok berat dan basah
- Lebih sering mengompol
- Kesulitan untuk tidur
- Demam
- Muntah
- Sembelit
- Penurunan berat badan
- Pertumbuhan tertunda
Diagnosis Diabetes Insipidus
Segera konsultasikan dengan dokter jika Anda mengalami gejala diabetes insipidus. Dokter akan bertanya tentang riwayat kesehatan Anda dan akan merekomendasikan beberapa tes untuk menemukan penyebab dari kondisi yang dialami. Tes juga dilakukan untuk mengetahui jenis diabetes insipidus.
Berikut adalah beberapa jenis tes yang mungkin dilakukan:
- Tes deprivasi air, tes ini mengharuskan Anda untuk sementara tidak mengonsumsi cairan dalam waktu beberapa jam untuk mengetahui respons tubuh Anda.
- Tes vasopressin, dilakukan dengan cara menyuntikkan APV dosis kecil untuk mengetahui bagaimana tubuh bereaksi terhadap hormon tersebut.
- Tes MRI, tes ini dilakukan untuk memindai otak apabila diduga terjadi kerusakan pada hipotalamus yang menyebabkan diabetes insipidus.
Perbedaan Diabetes Melitus dan Diabetes Insipidus
Pada dasarnya diabetes melitus dan diabetes insipidus memang tidak memiliki keterkaitan. Diabetes melitus atau dikenal juga dengan penyakit kencing manis adalah kondisi tingginya gula darah akibat tubuh yang tidak dapat memproses gula darah atau akibat kelainan produksi insulin.
Kedua kondisi ini tidak saling berhubungan dan tidak saling memengaruhi. Keduanya memang menimbulkan gejala cepat haus dan peningkatan produksi urin, namun dari segi penyebab dan penanganan, kedua penyakit ini berbeda.
Pengobatan Diabetes Insipidus
Pada dasarnya tidak ada pengobatan diabetes insipidus, pengobatan hanya dilakukan untuk meringankan gejalanya saja. Cara mengatasi gejala diabetes ini juga tentunya disesuaikan dengan jenis penyakit diabetes insipidus yang dialami.
1. Pengobatan diabetes insipidus kranial
Berikut adalah beberapa cara mengatasi diabetes insipidus kranial:
- Diabetes insipidus kranial ringan dapat diatasi dengan meningkatkan asupan air.
- Pemberian obat desmopressin pengganti hormon ADH atau AVP, dosisnya disesuaikan dengan jumlah hormon yang hilang, setiap pasien memiliki dosis yang berbeda-beda.
- Pemberian obat yang dapat meningkatkan ADH atau APV dalam tubuh (contohnya indomestasin dan chlorpropamide.
2. Pengobatan diabetes insipidus nefrogenik
Cara mengatasi diabetes insipidus nefrogenik berfokus pada masalah pada ginjal. Cara yang dapat dilakukan adalah seperti:
- Diet rendah garam untuk mengurangi produksi urin
- Minum cukup air untuk mencegah dehidrasi.
- Pemberian obat untuk mengatasi gejala seperti hydrochlorothiazide
- Menghentikan penggunaan obat tertentu berdasarkan saran dokter jika diabetes insipidus dipicu oleh penggunaan obat tertentu.
Sumber:
- Diabetes insipidus – https://www.nhs.uk/conditions/diabetes-insipidus/
- Diabetes insipidus – https://www.mayoclinic.org/diseases-conditions/diabetes-insipidus/symptoms-causes/syc-20351269
- Diabetes insipidus: The other diabetes – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743391/
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